WEST LAFAYETTE, Ind. — In 2018, approximately 324,000 men died from cancer in the United States. The combination of lung cancer, prostate cancer and colorectal cancer equated to half of those deaths.

Large percentages of each of these cancers can be prevented or treated if caught early. Now, Purdue University scientists have created a new therapy option that may help halt tumor growth in certain cancers such as prostate, which is among the most common types of cancer in men.

“We have designed a therapy that can help recruit immune cells to kill cancer and also help repair bone and tissues damaged by tumors,” said Marxa Figueiredo, associate professor of basic medical sciences in Purdue’s College of Veterinary Medicine, who helped lead the research team and is working with the Purdue Research Foundation Office of Technology Commercialization to patent the innovation. “One of the best features of this technology is that it shows great promise in enabling treatment for many other cancers and diseases that could benefit from halting tumor growth and promoting bone repair.”

The therapy technology is presented in the journal Molecular Therapy: Methods & Clinical Development.

The Purdue team used a protein called interleukin-27, or IL-27, which has shown promise in reducing tumor growth and helping stop cancer from spreading in the body. IL-27 is a cytokine, a kind of protein secreted by cells of the immune system that act as chemical messengers and can help the immune system target cancer and other diseases.

Chris Adam, 765-588-3341, cladam@prf.org

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